Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3750798 | 0.94 | ALDH1A1 (0.54) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL18239363 | 0.90 | ALDH1A1 (0.47) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL18228579 | 0.90 | ALDH1A1 (0.47) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL9529419 | 0.81 | KMT2A (0.56) | ALDH1A1MAPTCYP3A4PLOD2CYP2C9 | |
| SCHEMBL17842025 | 0.80 | KDM4E (0.47) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL17842028 | 0.80 | KDM4E (0.47) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| SCHEMBL273196 | 0.80 | HPGD (0.64) | ALDH1A1GAAMAPTNPSR1KMT2A | |
| SCHEMBL27961040 | 0.80 | HPGD (0.64) | ALDH1A1GAAMAPTNPSR1KMT2A | |
| Hydrochloric Acid SCHEMBL11023559 | 0.78 | TBXAS1 (0.60) | ALDH1A1GAAAPPHCAR3HCAR2 | |
| Water SCHEMBL9518556 | 0.78 | HPGD (0.61) | ALDH1A1GAAMAPTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |