SCHEMBL9529438

SCHEMBL9529438

CC1=CCN2CC=C(c3ccccc3)C1C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 18/20 0.37
CHRM4 P08173 18/20 0.37
CHRM5 P08912 18/20 0.37
CHRM1 P11229 18/20 0.37
CHRM3 P20309 18/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5542453 0.70 SLC6A2 (0.47)
SCHEMBL9532190 0.67 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8516623 0.59 CFTR (0.50)
SCHEMBL1673372 0.55 ALDH1A1 (0.40)
SCHEMBL16857693 0.55 ALDH1A1 (0.40)
SCHEMBL1673336 0.55 ALDH1A1 (0.40)
SCHEMBL31678783 0.54 CHRNA3 (0.36)
Biphenyl SCHEMBL8637370 0.53 ALDH1A1 (0.60)
Biphenyl SCHEMBL6943550 0.52 ALDH1A1 (0.69)
Biphenyl SCHEMBL323849 0.52 ALDH1A1 (0.69)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0556342-A1 NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME GYOGYSZERKUTATO INTEZET K.V. (HU) 1993-08-25 EP disclosed
WO-1992007854-A1 NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME GYÓGYSZERKUTATÓ INTÉZET KV. (HU) 1992-05-14 WO disclosed