Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 4/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | IL18 | Q14116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915586 | 1.00 | ABCC9 (0.46) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10341391 | 0.84 | ABCC9 (0.45) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10341392 | 0.84 | ABCC9 (0.45) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10859522 | 0.81 | MAPT (0.44) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10859517 | 0.81 | MAPT (0.44) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10453701 | 0.81 | ABCC9 (0.46) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10452496 | 0.79 | KDM1A (0.46) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10453550 | 0.79 | NOS3 (0.44) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10452497 | 0.79 | KDM1A (0.46) | ABCC9KCNJ11IDO1LMNAALDH1A1 | |
| SCHEMBL10452521 | 0.78 | GRIN2D (0.47) | ABCC9KCNJ11IDO1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |