Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639713 | 0.71 | CA1 (0.66) | HTTSMN1; SMN2CA1CA2CA12 | |
| SCHEMBL23384891 | 0.70 | CYP1B1 (0.41) | HTTSMN1; SMN2CA1CA2CYP1B1 | |
| Sulfuric Acid SCHEMBL20984569 | 0.69 | CA1 (0.58) | HTTSMN1; SMN2CA1CA2CA12 | |
| SCHEMBL30677196 | 0.69 | CYP1B1 (0.47) | HTTSMN1; SMN2CA1CA2CYP1B1 | |
| SCHEMBL3707004 | 0.69 | GRK2 (0.41) | HTTSMN1; SMN2CYP1B1CA9MMP2 | |
| SCHEMBL9529531 | 0.68 | CA1 (0.56) | HTTSMN1; SMN2CA1CA2CA12 | |
| SCHEMBL21626722 | 0.68 | GAA (0.59) | HTTSMN1; SMN2CYP1B1MAPTLMNA | |
| SCHEMBL30720835 | 0.67 | CYP1B1 (0.42) | HTTSMN1; SMN2CYP1B1MAPTLMNA | |
| Sulfuric Acid SCHEMBL28856222 | 0.67 | CA2 (0.50) | HTTSMN1; SMN2CA1CA2CA12 | |
| Sulfuric Acid SCHEMBL28200132 | 0.67 | CA1 (0.50) | HTTSMN1; SMN2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |