Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | CES1 | P23141 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217309 | 0.86 | MAPT (0.59) | MAPTCES2CES1MEN1KMT2A | |
| SCHEMBL22415506 | 0.81 | MAPT (0.53) | MAPTMEN1KMT2AMAOBAR | |
| SCHEMBL6219515 | 0.79 | MEN1 (0.56) | MAPTCES2CES1MEN1KMT2A | |
| SCHEMBL801254 | 0.78 | CES2 (0.61) | MAPTCES2CES1MEN1KMT2A | |
| SCHEMBL3310538 | 0.77 | CES2 (0.55) | CES2CES1MAOBARALDH1A1 | |
| SCHEMBL3310540 | 0.77 | CES2 (0.55) | CES2CES1MAOBARALDH1A1 | |
| SCHEMBL3310535 | 0.77 | CES2 (0.55) | CES2CES1MAOBARALDH1A1 | |
| SCHEMBL31563338 | 0.77 | ALDH1A1 (0.55) | MAPTCES2CES1MEN1KMT2A | |
| SCHEMBL31563343 | 0.77 | ALDH1A1 (0.55) | MAPTCES2CES1MEN1KMT2A | |
| SCHEMBL4004349 | 0.74 | CES2 (0.47) | MAPTCES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |