Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 19/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530240 | 0.78 | CA2 (0.66) | CA2 | |
| SCHEMBL9529742 | 0.74 | CA2 (0.60) | CA2 | |
| SCHEMBL2174766 | 0.64 | CA2 (0.45) | CA2CA4 | |
| SCHEMBL10513032 | 0.61 | CA2 (0.40) | CA2CA12CA1CA9 | |
| SCHEMBL10438198 | 0.60 | CA2 (0.67) | CA2 | |
| SCHEMBL9529564 | 0.59 | CA2 (1.00) | CA2 | |
| Hydrochloric Acid SCHEMBL9670398 | 0.59 | CA2 (0.68) | CA2 | |
| Hydrochloric Acid SCHEMBL9529625 | 0.58 | CA2 (1.00) | CA2 | |
| SCHEMBL2089671 | 0.58 | FBP1 (0.47) | CA2 | |
| SCHEMBL9529980 | 0.58 | CA2 (0.98) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307084-B1 | Substituted thieno(2,3-b)thiophene-2-sulfonamides as antiglaucoma agents | MERCK & CO INC (US) | 1993-12-15 | — | — | EP | claimed |