Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535615 | 0.84 | CDK1 (0.74) | CDK1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL9284934 | 0.82 | CDK1 (0.52) | CDK1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL10519893 | 0.79 | GAA (0.50) | CDK1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL8534243 | 0.77 | CDK1 (0.71) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL8782215 | 0.77 | CDK1 (0.62) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL5846414 | 0.77 | CDK1 (0.62) | CDK1GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL10396053 | 0.77 | CDK1 (0.62) | CDK1GAAMAPTTP53GLA | |
| SCHEMBL6912875 | 0.76 | CDK1 (0.73) | CDK1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9530201 | 0.76 | CA1 (0.44) | JUNNFKB1NFKB2RELAFOS | |
| SCHEMBL5847785 | 0.76 | CDK1 (0.61) | CDK1GAAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384602-B1 | N-substituted-3-[(2,3-dimethylmaleimido) amino]-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-08-04 | — | — | EP | disclosed |