SCHEMBL9530201

SCHEMBL9530201

CCOC(=O)c1ccc(NN2C(=O)C(C)=C(C)C2=O)cc1S(N)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.44
CA2 P00918 10/20 0.44
CA12 O43570 9/20 0.44
CA9 Q16790 8/20 0.44
FOS P01100 1/20 0.43
JUN P05412 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
CA7 P43166 2/20 0.40
CA14 Q9ULX7 1/20 0.40
KDM4E B2RXH2 2/20 0.39
CHRNA7 P36544 1/20 0.39
HPGD P15428 2/20 0.38
RECQL P46063 1/20 0.38
CA5A P35218 2/20 0.38
CA4 P22748 1/20 0.38
CA5B Q9Y2D0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9738324 0.89 CA2 (0.49) CA1CA2CA12CA9CA7
SCHEMBL9530660 0.84 ALDH1A1 (0.40) CA1CA2CA12CA9KMT2A
SCHEMBL9532475 0.83 CA1 (0.39) CA1CA2CA12CA9KMT2A
SCHEMBL9531300 0.82 CA1 (0.39) CA1CA2CA12CA9KMT2A
SCHEMBL9530711 0.81 CA1 (0.50) CA1CA2CA12CA9KMT2A
SCHEMBL8539079 0.78 CA1 (0.47) CA1CA2CA12CA9KMT2A
SCHEMBL9529913 0.76 CDK1 (0.53) FOSJUNNFKB1NFKB2RELA
SCHEMBL9531877 0.76 CA1 (0.55) CA1CA2CA12CA9KMT2A
SCHEMBL28090844 0.73 CA1 (0.52) CA1CA2CA12CA9KMT2A
SCHEMBL28732676 0.72 CA2 (0.51) CA1CA2CA12CA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384602-B1 N-substituted-3-[(2,3-dimethylmaleimido) amino]-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-08-04 EP disclosed
US-5129942-A For controlling monocotyledonous and dicotyledonous weeds on agricultural land KUREHA KAGAKU KOGYO K.K. (JP) 1992-07-14 US disclosed
US-5028255-A N-substituted-3-[(2,3-dimethylmaleimido)amino)]-benzenesulfonamide derivatives, hebicidal compositions and method of use KUREHA KAGAKU KOGYO K.K. (JP) 1991-07-02 US disclosed