Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530031 | 0.83 | MAPT (0.48) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL10807090 | 0.76 | LMNA (0.51) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL9529075 | 0.74 | MAPT (0.46) | MAPTALDH1A1GAAKDM4ELMNA | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL1500579 | 0.74 | KCNJ1 (0.68) | MAPTALDH1A1KDM4ELMNAMAPK1 | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL21644730 | 0.73 | KCNJ1 (0.64) | MAPTALDH1A1KDM4ELMNAMAPK1 | |
| Ethyl Acetate SCHEMBL28503452 | 0.73 | MAPK1 (0.71) | MAPTALDH1A1GAAKDM4ELMNA | |
| SCHEMBL11811932 | 0.72 | MAPT (0.54) | MAPTALDH1A1GAAKDM4ELMNA | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL21246856 | 0.72 | KCNJ1 (0.67) | MAPTALDH1A1KDM4ELMNAMAPK1 | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL27941051 | 0.72 | KCNJ1 (0.67) | MAPTALDH1A1KDM4ELMNAMAPK1 | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL28242787 | 0.72 | KCNJ1 (0.67) | MAPTALDH1A1KDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536424-A1 | NOVEL BENZOPYRAN DERIVATIVE | Japan Tobacco Inc. (JP) | 1993-04-14 | — | — | EP | disclosed |