Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Nitrobenzoic Acid SCHEMBL21644729 | 0.89 | TDP1 (0.66) | MAPK1MAPTLMNASMN1; SMN2MEN1 | |
| Ethyl Acetate SCHEMBL27606833 | 0.85 | ALOX5 (0.61) | MAPK1MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL27765 | 0.84 | MAPK1 (1.00) | MAPK1MAOBMAPTLMNASMN1; SMN2 | |
| Ethyl Acetate SCHEMBL27930046 | 0.84 | SMN1; SMN2 (0.50) | MAPK1MAPTLMNASMN1; SMN2KMT2A | |
| Nitrobenzene SCHEMBL9326043 | 0.83 | ALDH1A1 (0.55) | MAPK1MAPTLMNASMN1; SMN2MEN1 | |
| Methyl Alcohol SCHEMBL28098714 | 0.82 | MAPK1 (0.96) | MAPK1MAOBMAPTLMNASMN1; SMN2 | |
| Bromide SCHEMBL8031021 | 0.82 | MAPK1 (0.96) | MAPK1MAOBMAPTLMNASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL17180526 | 0.82 | MAPK1 (0.96) | MAPK1MAOBMAPTLMNASMN1; SMN2 | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL1500579 | 0.81 | KCNJ1 (0.68) | MAPK1MAPTLMNAMEN1KMT2A | |
| Ethyl Acetate SCHEMBL27911725 | 0.81 | LMNA (0.48) | MAPK1MAOBMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112014338-A | Paraoxonase-1 activity detection kit and application thereof | 武汉生之源生物科技股份有限公司 | 2020-12-01 | — | — | CN | disclosed |