Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846078 | 0.81 | KDM4E (0.50) | NPC1C1RPDE10AELANERAB9A | |
| SCHEMBL5788551 | 0.76 | CYP1A2 (0.56) | MBNL1NPC1ADORA2ARAB9AL3MBTL1 | |
| SCHEMBL30476648 | 0.76 | CYP1A2 (0.56) | MBNL1NPC1ADORA2ARAB9AL3MBTL1 | |
| SCHEMBL1651399 | 0.76 | PDE10A (0.44) | NPC1ADORA2APDE10ARAB9AL3MBTL1 | |
| SCHEMBL11389060 | 0.75 | KDM4E (0.41) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL9187882 | 0.71 | MEN1 (0.50) | NPC1ADORA2APDE10ARAB9AL3MBTL1 | |
| SCHEMBL17363620 | 0.70 | MBNL1 (0.61) | MBNL1NPC1ADORA2AC1RRAB9A | |
| SCHEMBL8776992 | 0.70 | MBNL1 (0.56) | MBNL1NPC1ADORA2APDE10ARAB9A | |
| SCHEMBL29839891 | 0.69 | MBNL1 (0.47) | MBNL1NPC1ADORA2ARAB9AL3MBTL1 | |
| SCHEMBL8775659 | 0.69 | NPC1 (0.52) | MBNL1NPC1PDE10AELANERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | claimed |