Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530110 | 0.81 | MBNL1 (0.50) | KDM4EALDH1A1PDE10AELANEC1R | |
| SCHEMBL1651399 | 0.76 | PDE10A (0.44) | KDM4EALDH1A1GLAPDE10AKMT2A | |
| SCHEMBL28110411 | 0.76 | CYP1A2 (0.56) | KDM4EALDH1A1GLAPDE10AKMT2A | |
| SCHEMBL6545475 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1GLAELANECNR1 | |
| SCHEMBL9187882 | 0.71 | MEN1 (0.50) | KDM4EALDH1A1GLAPDE10AKMT2A | |
| SCHEMBL8776689 | 0.70 | ALDH1A1 (0.43) | KDM4EALDH1A1GLAPDE10AELANE | |
| SCHEMBL8775144 | 0.69 | CYP1A2 (0.44) | KDM4EALDH1A1GLAPDE10AELANE | |
| SCHEMBL3170374 | 0.68 | ALDH1A1 (0.43) | KDM4EALDH1A1GLAKMT2ANPC1 | |
| SCHEMBL3244662 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1GLA | |
| SCHEMBL11389060 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1GLAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089981-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS. | Elan Pharmaceuticals, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067220-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | disclosed |