Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530336 | 1.00 | LTA4H (0.39) | LTA4HMAPTL3MBTL1ANPEPATM | |
| SCHEMBL7110744 | 0.72 | MAOA (0.40) | — | |
| SCHEMBL29440588 | 0.68 | LTA4H (0.31) | LTA4H | |
| Phenylalanine Methyl Ester SCHEMBL186022 | 0.68 | SLC7A5 (0.63) | LTA4HANPEPATMCYP2C19MEN1 | |
| Phenylalanine Methyl Ester SCHEMBL74887 | 0.68 | SLC7A5 (0.63) | LTA4HANPEPATMCYP2C19MEN1 | |
| Phenylalanine Methyl Ester SCHEMBL74888 | 0.68 | SLC7A5 (0.63) | LTA4HANPEPATMCYP2C19MEN1 | |
| Phenylalanine Methyl Ester SCHEMBL27880854 | 0.68 | SLC7A5 (0.63) | LTA4HANPEPATMCYP2C19MEN1 | |
| SCHEMBL25522005 | 0.68 | LTA4H (0.56) | LTA4HATM | |
| Phenylalanine Methyl Ester SCHEMBL2728392 | 0.67 | SLC7A5 (0.61) | LTA4HANPEPATMCYP2C19MEN1 | |
| Phenylalanine Methyl Ester SCHEMBL2237414 | 0.67 | SLC7A5 (0.61) | LTA4HANPEPATMCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515548-A4 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | — | 1993-03-10 | — | — | EP | disclosed |
| US-5183810-A | Hyptoensive agents | MERCK & CO., INC. (US) | 1993-02-02 | — | — | US | disclosed |
| EP-0515548-A1 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012002-A1 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO., INC. (US) | 1991-08-22 | — | — | WO | disclosed |