Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27753327 | 0.95 | LMNA (0.55) | LMNAACE2OPRM1PRKD3PRKCG | |
| SCHEMBL27345411 | 0.95 | OPRM1 (0.44) | LMNAACE2OPRM1PRKD3PRKCG | |
| SCHEMBL27470379 | 0.93 | ACE2 (0.45) | LMNAACE2OPRM1PRKD3PRKCG | |
| SCHEMBL27223874 | 0.93 | ACE2 (0.45) | LMNAACE2OPRM1PRKD3PRKCG | |
| SCHEMBL1645053 | 0.93 | ACE2 (0.45) | LMNAACE2OPRM1PRKD3PRKCG | |
| SCHEMBL28031697 | 0.91 | ACE2 (0.52) | LMNAACE2OPRM1PRKD3PRKCG | |
| SCHEMBL1873151 | 0.91 | OPRM1 (0.48) | LMNAACE2OPRM1PRKD3PRKCG | |
| SCHEMBL671349 | 0.88 | ACE2 (0.48) | LMNAACE2OPRM1SPHK1ADH1B | |
| SCHEMBL2852595 | 0.88 | LMNA (0.38) | LMNAACE2OPRM1DNM1FDPS | |
| SCHEMBL4274565 | 0.88 | ACE2 (0.48) | LMNAACE2OPRM1SPHK1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203093-B1 | MONOCLONAL ANTIBODIES AGAINST ALVEOLAR SURFACTANT PROTEIN | SCIOS NOVA INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4851333-A | Method and composition for the detection and diagnosis of Legionella pneumophila | GENETIC SYSTEMS CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| US-4656253-A | Monoclonal antibodies against alveolar surfactant protein | CALIFORNIA BIOTECHOLOGY, INC. (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0203093-A4 | MONOCLONAL ANTIBODIES AGAINST ALVEOLAR SURFACTANT PROTEIN. | CALIFORNIA BIOTECHNOLOGY INC (US) | 1987-03-03 | — | — | EP | disclosed |
| EP-0203093-A1 | MONOCLONAL ANTIBODIES AGAINST ALVEOLAR SURFACTANT PROTEIN. | CALIFORNIA BIOTECHNOLOGY INC (US) | 1986-12-03 | — | — | EP | disclosed |
| WO-1986002558-A1 | MONOCLONAL ANTIBODIES AGAINST ALVEOLAR SURFACTANT PROTEIN | CALIFORNIA BIOTECHNOLOGY, INC. (US) | 1986-05-09 | — | — | WO | disclosed |
| US-4562003-A | Monoclonal antibodies against alveolar surfactant protein | CALIFORNIA BIOTECHNOLOGY, INC. (US) | 1985-12-31 | — | — | US | disclosed |