Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 9/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259475 | 0.70 | BRS3 (0.44) | BRS3CYP1A2PPARG | |
| SCHEMBL9530397 | 0.67 | BRS3 (0.40) | BRS3CYP1A2PPARGPLA2G10PLA2G2A | |
| SCHEMBL9025505 | 0.65 | BRS3 (0.37) | BRS3KDM5BKDM6BKDM4AKDM4D | |
| SCHEMBL8954220 | 0.64 | AGTR1 (0.51) | — | |
| SCHEMBL10174226 | 0.63 | TSHR (0.50) | — | |
| SCHEMBL9512932 | 0.63 | F2RL1 (0.34) | BRS3CYP1A2KDM5A | |
| SCHEMBL265063 | 0.63 | CYP1A2 (0.83) | CYP1A2PPARG | |
| SCHEMBL265514 | 0.63 | CYP1A2 (0.83) | CYP1A2PPARG | |
| SCHEMBL491524 | 0.63 | CYP1A2 (0.83) | CYP1A2PPARG | |
| SCHEMBL1596298 | 0.63 | SMN1; SMN2 (0.61) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541705-A4 | SUBSTITUTED 1H-IMIDAZOL-5-YL)ALKANOIC ACIDS | — | 1993-11-10 | — | — | EP | disclosed |
| EP-0541705-A1 | SUBSTITUTED 1H-IMIDAZOL-5-YL]ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-19 | — | — | EP | disclosed |