Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 9/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954337 | 0.75 | EPHX2 (0.38) | CYP1A2PTGESALOX5 | |
| SCHEMBL9529061 | 0.75 | CYP1A2 (0.39) | MMECYP1A2PTGESALOX5PPARG | |
| SCHEMBL9532826 | 0.73 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL8954220 | 0.72 | AGTR1 (0.51) | AGTR1 | |
| SCHEMBL9529092 | 0.67 | PARP1 (0.35) | — | |
| SCHEMBL9530398 | 0.67 | BRS3 (0.42) | BRS3PLA2G10PLA2G2ACYP1A2PPARG | |
| SCHEMBL8741267 | 0.67 | PARP1 (0.42) | BRS3PTGESALOX5PPARG | |
| SCHEMBL29151819 | 0.66 | HNF4A (0.62) | PLA2G10PLA2G2A | |
| SCHEMBL28161278 | 0.66 | PARP1 (0.41) | — | |
| SCHEMBL9536151 | 0.66 | MME (0.40) | MMEAGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541705-A4 | SUBSTITUTED 1H-IMIDAZOL-5-YL)ALKANOIC ACIDS | — | 1993-11-10 | — | — | EP | disclosed |
| EP-0541705-A1 | SUBSTITUTED 1H-IMIDAZOL-5-YL]ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-19 | — | — | EP | disclosed |