SCHEMBL9530404

SCHEMBL9530404

CC(=O)OC(C(=O)OC(C)(C)C)N1C(=O)CCC1=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.31
ELANE P08246 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12541030 0.78 ALDH1A1 (0.38) GLA
SCHEMBL9530724 0.76 GLA (0.34) GLA
SCHEMBL542453 0.75 ELANE (0.33) ELANE
SCHEMBL18206515 0.70
SCHEMBL18206513 0.70
SCHEMBL12482671 0.70 GRIN2B (0.35) ELANE
SCHEMBL18206308 0.69
SCHEMBL18206575 0.69
SCHEMBL18206144 0.69
SCHEMBL18206577 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252744-B1 3-Beta-(3,4-disubstituted succinimido)azetidinones LILLY CO ELI (US) 1993-12-15 EP disclosed
US-4734498-A 3β-succinimidoazetidinones as chiral intermediates ELI LILLY AND COMPANY (US) 1988-03-29 US disclosed
EP-0252744-A2 3-Beta-(3,4-disubstituted succinimido)azetidinones ELI LILLY AND COMPANY (US) 1988-01-13 EP disclosed