Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12541030 | 0.83 | ALDH1A1 (0.38) | GLATSHRKMT2AATMCYP2D6 | |
| SCHEMBL9530404 | 0.76 | GLA (0.31) | GLA | |
| SCHEMBL25267755 | 0.66 | ALDH1A1 (0.39) | KMT2AATMALDH1A1PKM | |
| SCHEMBL25267754 | 0.66 | ALDH1A1 (0.39) | KMT2AATMALDH1A1PKM | |
| SCHEMBL9476063 | 0.66 | LMNA (0.47) | GLATSHRKMT2ACYP2D6CYP2C9 | |
| SCHEMBL28370260 | 0.64 | TSHR (0.54) | GLATSHRCYP2D6ALDH1A1CHRM2 | |
| SCHEMBL25391535 | 0.64 | GLA (0.35) | GLATSHRKMT2AATMCYP2D6 | |
| SCHEMBL18020563 | 0.63 | SLC1A2 (0.45) | GLAKMT2AATMCYP2D6CYP2C9 | |
| SCHEMBL18908216 | 0.63 | GLA (0.34) | GLATSHR | |
| SCHEMBL18206954 | 0.62 | TSHR (0.35) | GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252744-B1 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | LILLY CO ELI (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4734498-A | 3β-succinimidoazetidinones as chiral intermediates | ELI LILLY AND COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0252744-A2 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |