Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | TTPA | P49638 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487350 | 0.82 | MEN1 (0.52) | MEN1KMT2AMAPTTDP1PPARG | |
| SCHEMBL9533463 | 0.82 | PPARG (0.42) | MEN1KMT2AMAPTTDP1PPARG | |
| SCHEMBL9530822 | 0.81 | KDM4E (0.35) | MEN1KMT2AMAPTTDP1PPARG | |
| SCHEMBL10640306 | 0.81 | AKT1 (0.39) | MEN1KMT2AMAPTTDP1PPARG | |
| SCHEMBL9631957 | 0.77 | AKT1 (0.37) | PPARGAKT1PPARAPPARD | |
| SCHEMBL9530470 | 0.76 | MAPT (0.50) | MEN1KMT2AMAPTTDP1PPARG | |
| SCHEMBL7986932 | 0.74 | MAPT (0.61) | MEN1KMT2AMAPTTDP1PPARG | |
| SCHEMBL9632651 | 0.74 | AKT1 (0.37) | PPARGAKT1PPARAPPARD | |
| SCHEMBL10640341 | 0.73 | MEN1 (0.56) | MEN1KMT2AMAPTTDP1PDE4A | |
| SCHEMBL10636591 | 0.73 | MEN1 (0.44) | MEN1KMT2AMAPTTDP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |