Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.35 |
| ▸ | GAA | P10253 | 9/20 | 0.35 |
| ▸ | HPGD | P15428 | 8/20 | 0.35 |
| ▸ | GLA | P06280 | 6/20 | 0.35 |
| ▸ | CASP1 | P29466 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530770 | 0.87 | MAPT (0.42) | KDM4EALDH1A1MAOBMEN1MAPT | |
| SCHEMBL9533035 | 0.84 | ESR1 (0.40) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9530585 | 0.81 | MEN1 (0.40) | MEN1MAPTKMT2ATDP1AKT1 | |
| SCHEMBL7125937 | 0.80 | MEN1 (0.36) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9533181 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL10656598 | 0.78 | MAOB (0.36) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL10640498 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9630958 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL8980246 | 0.74 | MEN1 (0.44) | KDM4EALDH1A1GAAHPGDCASP1 | |
| SCHEMBL7487350 | 0.73 | MEN1 (0.52) | MEN1MAPTKMT2ATDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |