Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.36 |
| ▸ | KDM3B | Q7LBC6 | 2/20 | 0.36 |
| ▸ | HIF1AN | Q9NWT6 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536679 | 0.89 | MAPT (0.43) | HTTTSHRKDM4EMEN1GAA | |
| SCHEMBL9533481 | 0.86 | MAPT (0.41) | HTTTSHRKDM4EMEN1GAA | |
| SCHEMBL9532541 | 0.83 | MAPT (0.46) | HTTNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9534195 | 0.81 | ALDH1A1 (0.44) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9531029 | 0.81 | ALDH1A1 (0.44) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9532867 | 0.81 | MAPT (0.44) | HTTMEN1KMT2AHSD17B10NPC1 | |
| SCHEMBL10693329 | 0.79 | MAPT (0.42) | HTTL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL9531971 | 0.78 | GPR84 (0.46) | HTTKDM4ENPC1MAPTRAB9A | |
| SCHEMBL9530754 | 0.77 | TSHR (0.43) | HTTTSHRKDM4EMEN1GAA | |
| SCHEMBL9531893 | 0.77 | KDM4E (0.44) | HTTTSHRKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |