Fluoride

Fluoride

SCHEMBL9530759

CC(C)C1CNc2ccccc2N1.F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
BRD4 O60885 4/20 0.34
CREBBP Q92793 4/20 0.34
EP300 Q09472 1/20 0.34
BRPF1 P55201 1/20 0.33
GAA P10253 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 2/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
GFER P55789 1/20 0.32
JAK2 O60674 1/20 0.31
PRCP P42785 1/20 0.31
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30
PRKD3 O94806 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28517927 1.00 ALOX5 (0.36) ALOX5BRD4CREBBPEP300BRPF1
SCHEMBL4907952 0.81 ALOX5 (0.34) ALOX5BRD4CREBBPEP300BRPF1
SCHEMBL30570961 0.72 BRD4 (0.50) BRD4CREBBPEP300BRPF1GAA
SCHEMBL19225173 0.72 BRD4 (0.50) BRD4CREBBPEP300BRPF1GAA
SCHEMBL2723593 0.72 BRD4 (0.50) BRD4CREBBPEP300BRPF1GAA
SCHEMBL29898376 0.72 BRD4 (0.50) BRD4CREBBPEP300BRPF1GAA
SCHEMBL15508279 0.72 BRD4 (0.50) BRD4CREBBPEP300BRPF1GAA
SCHEMBL6926769 0.72 CREBBP (0.34) BRD4CREBBPEP300BRPF1GAA
SCHEMBL27322746 0.72 MEN1 (0.33) BRD4CREBBPEP300GAAMEN1
SCHEMBL3427321 0.72 GAA (0.50) ALOX5BRD4CREBBPEP300GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5162459-A None JP disclosed
JP-3036084-A None JP disclosed
CN-110446616-B Thermosensitive recording medium and article 株式会社理光 2021-06-01 CN disclosed
US-20210008917-A1 THERMOSENSITIVE RECORDING MEDIUM, THERMOSENSITIVE RECORDING MEDIUM PRODUCING METHOD, AND ARTICLE RICOH COMPANY, LTD. (JP) 2021-01-14 US disclosed
US-20200384789-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH COMPANY, LTD. (JP) 2020-12-10 US disclosed
EP-3727866-A1 THERMOSENSITIVE RECORDING MEDIUM, THERMOSENSITIVE RECORDING MEDIUM PRODUCING METHOD, AND ARTICLE Ricoh Company, Ltd. (JP) 2020-10-28 EP disclosed
CN-111556812-A Thermosensitive recording medium, thermosensitive recording medium production method and product 株式会社理光 2020-08-18 CN disclosed
EP-3600901-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE Ricoh Company, Ltd. (JP) 2020-02-05 EP disclosed
JP-H05162459-A RECORDING MATERIAL NIPPON KAYAKU CO LTD 1993-06-29 JP disclosed
JP-H0336084-A RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1991-02-15 JP disclosed