Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.75 |
| ▸ | MEN1 | O00255 | 6/20 | 0.75 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | TDO2 | P48775 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368151 | 0.88 | ALDH1A1 (0.62) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29149105 | 0.87 | KMT2A (0.73) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29149100 | 0.85 | KMT2A (0.70) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5320644 | 0.84 | MEN1 (0.54) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31556010 | 0.83 | KMT2A (0.67) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7046987 | 0.83 | ALDH1A1 (0.72) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7131385 | 0.82 | IDO1 (0.75) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL31555998 | 0.80 | KMT2A (0.74) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12387924 | 0.80 | KDM4E (0.63) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7468407 | 0.79 | KMT2A (0.59) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290915-B1 | FLAVONE-3-CARBOXYLIC-ACID COMPOUNDS, AND PROCESS, INTERMEDIATES FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Kali-Chemie Pharma GmbH (DE) | 1993-07-14 | — | — | EP | disclosed |
| US-5013852-A | Antiinflammatory | KALI-CHEMIE PHARMA GMBH (DE) | 1991-05-07 | — | — | US | disclosed |
| US-4886806-A | ANTIINFLAMMATORY AGENTS | KALI-CHEMIE PHARMA GMBH (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0290915-A2 | Flavone-3-carboxylic-acid compounds, and process, intermediates for their preparation and medicines containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1988-11-17 | — | — | EP | disclosed |