Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346443 | 0.86 | MEN1 (0.73) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL9530950 | 0.84 | KMT2A (0.75) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL5342594 | 0.83 | NPC1 (0.64) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL5710003 | 0.82 | TUBB4A (0.59) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL30375359 | 0.82 | TUBB4A (0.59) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7046987 | 0.82 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7549549 | 0.78 | HSP90AB1 (0.70) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7468407 | 0.78 | KMT2A (0.59) | MEN1KMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL9343430 | 0.77 | MEN1 (0.67) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL1259813 | 0.77 | NPC1 (0.65) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807408-B1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL SCIENT IND RES (IN) | 2016-06-08 | — | — | EP | disclosed |
| EP-1807408-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | Council of Scientific and Industrial Research (IN) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006040621-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-04-20 | — | — | WO | disclosed |