Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | F2R | P25116 | 4/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402943 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL7364611 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL525132 | 0.90 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL6070988 | 0.82 | RECQL (0.61) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL523930 | 0.82 | MAPT (0.68) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL5818378 | 0.82 | RECQL (0.61) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL523929 | 0.82 | MAPT (0.68) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL10735227 | 0.80 | MAPT (0.57) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL10735224 | 0.80 | MAPT (0.57) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA | |
| SCHEMBL1879894 | 0.79 | MAPT (0.63) | ALDH1A1MAPTSMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208846-B1 | [7-(3-Disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines | AMERICAN CYANAMID CO (US) | 1993-11-18 | — | — | EP | disclosed |