Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 2/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10475163 | 0.83 | HDAC6 (0.45) | MAPTALDH1A1HTTHPGDHDAC6 | |
| SCHEMBL13750359 | 0.79 | MAPT (0.51) | MAPTALDH1A1HTTHPGDHDAC6 | |
| SCHEMBL13750352 | 0.78 | BCHE (0.52) | MAPTALDH1A1HTTHPGDHDAC6 | |
| SCHEMBL13750362 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1HTTHPGDHDAC6 | |
| SCHEMBL13750330 | 0.76 | MAPT (0.40) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL13750438 | 0.75 | BCHE (0.55) | MAPTALDH1A1HTTHPGDHDAC6 | |
| SCHEMBL13757997 | 0.75 | ALDH1A1 (0.45) | MAPTALDH1A1HTTHPGDHDAC6 | |
| SCHEMBL13750355 | 0.75 | ALDH1A1 (0.51) | MAPTALDH1A1HTTHPGDHDAC6 | |
| SCHEMBL13750343 | 0.73 | BCHE (0.55) | MAPTALDH1A1HTTHPGDMEN1 | |
| SCHEMBL9340150 | 0.73 | MAPT (0.50) | MAPTALDH1A1HTTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569688-B2 | Propane-1, 3-dione derivative | ASTELLAS PHARMA INC. (JP) | 2009-08-04 | — | — | US | disclosed |
| EP-0332044-B1 | HETEROCYCLIC COMPOUNDS CONTAINING 4,6-BIS-TRICHLOROMETHYL-S-TRIAZIN-2-YL GROUPS, PROCESS FOR THEIR PREPARATION AND PHOTOSENSITIVE MIXTURE CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5055579-A | Photoinitiators; high sensitivity in visible spectral range; stability | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |
| EP-0332044-A1 | Heterocyclic compounds containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-13 | — | — | EP | disclosed |