Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13750359 | 0.87 | MAPT (0.51) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL13750352 | 0.86 | BCHE (0.52) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL13750362 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL13750438 | 0.82 | BCHE (0.55) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL10475163 | 0.81 | HDAC6 (0.45) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL13750343 | 0.81 | BCHE (0.55) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL13825587 | 0.75 | MAPT (0.51) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL9531247 | 0.75 | MAPT (0.39) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL13750429 | 0.75 | LMNA (0.45) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL13750447 | 0.74 | MAPT (0.47) | ALDH1A1MAPTHTTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569688-B2 | Propane-1, 3-dione derivative | ASTELLAS PHARMA INC. (JP) | 2009-08-04 | — | — | US | disclosed |