⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531289 | 1.00 | — | — | |
| SCHEMBL9529750 | 1.00 | — | — | |
| SCHEMBL9529278 | 0.87 | HPGD (0.42) | — | |
| SCHEMBL9529285 | 0.87 | HPGD (0.42) | — | |
| SCHEMBL9529273 | 0.87 | HPGD (0.42) | — | |
| Hydrochloric Acid SCHEMBL9528539 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL9528547 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL9528920 | 0.85 | — | — | |
| SCHEMBL9531297 | 0.84 | — | — | |
| SCHEMBL9527728 | 0.84 | NPC1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |