Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530063 | 0.85 | — | — | |
| SCHEMBL9529750 | 0.84 | — | — | |
| SCHEMBL9531283 | 0.84 | — | — | |
| SCHEMBL9531289 | 0.84 | — | — | |
| SCHEMBL9530037 | 0.84 | ALDH1A1 (0.39) | NPC1RAB9ATLR2PPARA | |
| SCHEMBL9532287 | 0.83 | — | — | |
| SCHEMBL9527949 | 0.77 | — | — | |
| SCHEMBL9529528 | 0.76 | PPARA (0.37) | PPARA | |
| SCHEMBL9529530 | 0.76 | PPARA (0.37) | PPARA | |
| SCHEMBL9528943 | 0.71 | CTSK (0.34) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |