Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529278 | 1.00 | HPGD (0.42) | HPGDHSD17B10TLR2CTSKALOX12 | |
| SCHEMBL9529285 | 1.00 | HPGD (0.42) | HPGDHSD17B10TLR2CTSKALOX12 | |
| SCHEMBL9530037 | 0.87 | ALDH1A1 (0.39) | HPGDHSD17B10TLR2CTSKMEN1 | |
| SCHEMBL9531283 | 0.87 | — | — | |
| SCHEMBL9531289 | 0.87 | — | — | |
| SCHEMBL9529750 | 0.87 | — | — | |
| SCHEMBL9693316 | 0.84 | HPGD (0.48) | HPGDHSD17B10 | |
| SCHEMBL9693970 | 0.83 | HPGD (0.50) | HPGDHSD17B10TLR2CTSKALOX12 | |
| SCHEMBL9531777 | 0.83 | PLA2G2A (0.39) | FAAH | |
| SCHEMBL9528828 | 0.83 | ATM (0.41) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |