Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531252 | 1.00 | HTR4 (0.65) | HTR4KCNH2 | |
| SCHEMBL9531399 | 1.00 | HTR4 (0.65) | HTR4KCNH2 | |
| SCHEMBL28920790 | 0.96 | HTR4 (0.70) | HTR4KCNH2 | |
| SCHEMBL6839835 | 0.96 | HTR4 (0.70) | HTR4KCNH2 | |
| SCHEMBL9790073 | 0.89 | HTR4 (0.76) | HTR4KCNH2 | |
| SCHEMBL9790086 | 0.89 | HTR4 (0.76) | HTR4KCNH2 | |
| SCHEMBL9790079 | 0.89 | HTR4 (0.76) | HTR4KCNH2 | |
| SCHEMBL4342483 | 0.85 | HTR4 (0.87) | HTR4KCNH2 | |
| SCHEMBL4333280 | 0.85 | HTR4 (0.87) | HTR4KCNH2 | |
| SCHEMBL9530810 | 0.85 | HTR4 (0.51) | HTR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251417-B1 | 4-(AROYLAMINO) PIPERIDINEBUTANAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-04-14 | — | — | EP | disclosed |