Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790079 | 1.00 | HTR4 (0.76) | HTR4KCNH2 | |
| SCHEMBL9790086 | 1.00 | HTR4 (0.76) | HTR4KCNH2 | |
| SCHEMBL6843940 | 0.96 | HTR4 (0.81) | HTR4KCNH2 | |
| SCHEMBL9021743 | 0.96 | HTR4 (0.81) | HTR4KCNH2 | |
| SCHEMBL6843942 | 0.96 | HTR4 (0.81) | HTR4KCNH2 | |
| SCHEMBL9531399 | 0.89 | HTR4 (0.65) | HTR4KCNH2 | |
| SCHEMBL9531252 | 0.89 | HTR4 (0.65) | HTR4KCNH2 | |
| SCHEMBL9531408 | 0.89 | HTR4 (0.65) | HTR4KCNH2 | |
| SCHEMBL3317348 | 0.86 | HTR4 (1.00) | HTR4KCNH2 | |
| SCHEMBL3317350 | 0.86 | HTR4 (1.00) | HTR4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990521-A | Treating diarhea | JANSSEN PHARMACEUTICA (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0251417-A2 | 4-(aroylamino) piperidinebutanamide derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-01-07 | — | — | EP | disclosed |