Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532881 | 0.85 | HTR1A (0.39) | HTR1AMAOBPDPK1MTNR1AMTNR1B | |
| SCHEMBL9531143 | 0.80 | KDM4E (0.39) | HTR1A | |
| SCHEMBL15049696 | 0.74 | MAOB (0.39) | MAOBPDPK1MTNR1AMTNR1BDRD2 | |
| SCHEMBL3653493 | 0.74 | PLAU (0.38) | HTR1AMAOBPDPK1PLAUSIGMAR1 | |
| SCHEMBL18378200 | 0.69 | PLAU (0.38) | MAOBPDPK1PLAUGRIN2B | |
| SCHEMBL18243384 | 0.69 | PLAU (0.38) | MAOBPDPK1SRD5A1PLAUGRIN2B | |
| SCHEMBL17765413 | 0.69 | PLAU (0.38) | MAOBPDPK1PLAUGRIN2B | |
| SCHEMBL9532783 | 0.69 | DRD3 (0.39) | HTR1ASIGMAR1 | |
| SCHEMBL7808997 | 0.69 | MAOB (0.36) | MAOBPDPK1DRD2PLAUSIGMAR1 | |
| SCHEMBL18243175 | 0.65 | PLAU (0.34) | MAOBPDPK1MTNR1AMTNR1BPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |