Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531143 | 0.84 | KDM4E (0.39) | DRD3KDM4EL3MBTL1PSEN1PSEN2 | |
| SCHEMBL9532881 | 0.81 | HTR1A (0.39) | HTR1ASIGMAR1 | |
| SCHEMBL28306580 | 0.81 | DRD3 (0.37) | DRD3KDM4EL3MBTL1HTR1AIDO1 | |
| SCHEMBL9531644 | 0.69 | HTR1A (0.38) | HTR1ASIGMAR1 | |
| SCHEMBL9531823 | 0.69 | POLB (0.38) | KDM4EALDH1A1 | |
| SCHEMBL17765425 | 0.69 | IDO1 (0.38) | KDM4EL3MBTL1IDO1 | |
| SCHEMBL3916886 | 0.69 | FYN (0.57) | DRD3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22554804 | 0.69 | CYP19A1 (0.39) | KDM4EL3MBTL1IDO1 | |
| SCHEMBL1702930 | 0.69 | CYP19A1 (0.39) | KDM4EL3MBTL1IDO1 | |
| SCHEMBL7467962 | 0.68 | DRD3 (0.38) | DRD3KDM4EL3MBTL1HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |