Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532070 | 1.00 | PPARA (0.41) | PPARACYP2C9TSHRPLA2G2ASMPD1 | |
| SCHEMBL9531869 | 0.86 | PPARA (0.39) | PPARATSHRPLA2G2ASMPD1CNR2 | |
| SCHEMBL9531863 | 0.86 | PPARA (0.39) | PPARATSHRPLA2G2ASMPD1CNR2 | |
| SCHEMBL9528909 | 0.85 | PPARA (0.43) | PPARATSHRSMPD1CNR2ALDH1A1 | |
| SCHEMBL9528916 | 0.85 | PPARA (0.43) | PPARATSHRSMPD1CNR2ALDH1A1 | |
| SCHEMBL9529530 | 0.84 | PPARA (0.37) | PPARACYP2C9PLA2G2ASMPD1CNR2 | |
| SCHEMBL9529528 | 0.84 | PPARA (0.37) | PPARACYP2C9PLA2G2ASMPD1CNR2 | |
| SCHEMBL9529381 | 0.76 | PLA2G2A (0.41) | PPARAPLA2G2ASMPD1CNR2 | |
| SCHEMBL9529384 | 0.76 | PLA2G2A (0.41) | PPARAPLA2G2ASMPD1CNR2 | |
| SCHEMBL10770807 | 0.73 | PPARA (0.38) | PPARATSHRSMPD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |