Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529711 | 0.83 | KMT2A (0.50) | TBXAS1MAPK1TDP1TBXA2RALDH1A1 | |
| SCHEMBL9528581 | 0.82 | TBXAS1 (0.59) | TBXAS1TBXA2RALDH1A1MEN1KMT2A | |
| SCHEMBL9528365 | 0.81 | TBXAS1 (0.58) | TBXAS1TDP1TBXA2RALDH1A1MEN1 | |
| SCHEMBL9532300 | 0.80 | TBXAS1 (0.57) | TBXAS1TDP1TBXA2RALDH1A1MEN1 | |
| SCHEMBL9528541 | 0.78 | TBXAS1 (0.53) | TBXAS1TBXA2RALDH1A1MEN1KMT2A | |
| SCHEMBL9527676 | 0.77 | TBXAS1 (0.63) | TBXAS1TBXA2RALDH1A1KMT2A | |
| SCHEMBL9529664 | 0.77 | TBXAS1 (0.63) | TBXAS1TBXA2RALDH1A1KMT2A | |
| SCHEMBL9528664 | 0.77 | TBXAS1 (0.60) | TBXAS1TBXA2RALDH1A1MEN1KMT2A | |
| SCHEMBL9529151 | 0.77 | TBXAS1 (0.60) | TBXAS1TBXA2RALDH1A1MEN1KMT2A | |
| SCHEMBL9532127 | 0.76 | TBXAS1 (0.62) | TBXAS1TBXA2RALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |