Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927137 | 0.73 | LMNA (0.54) | PTPN1ACP1CDC25BBACE1GLA | |
| SCHEMBL31603 | 0.72 | BACE1 (0.44) | PTPN1ACP1CDC25BBACE1GLA | |
| SCHEMBL7243740 | 0.71 | PTPN1 (0.49) | PTPN1ACP1CDC25BBACE1HSD17B10 | |
| SCHEMBL3789174 | 0.70 | PTPN1 (0.51) | PTPN1ACP1CDC25BHSD17B10 | |
| SCHEMBL3782935 | 0.70 | PTPN1 (0.51) | PTPN1ACP1CDC25BHSD17B10 | |
| SCHEMBL20826897 | 0.68 | KDM4E (0.50) | PTPN1ACP1CDC25BBACE1GLA | |
| SCHEMBL4459751 | 0.67 | BACE1 (0.46) | PTPN1ACP1CDC25BBACE1GLA | |
| SCHEMBL1012423 | 0.67 | BACE1 (0.46) | PTPN1BACE1GLANPSR1 | |
| SCHEMBL29663487 | 0.67 | BACE1 (0.40) | PTPN1ACP1CDC25BBACE1GLA | |
| SCHEMBL21999082 | 0.66 | GLA (0.43) | PTPN1ACP1CDC25BBACE1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525123-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES. | UPJOHN CO (US) | 1993-02-03 | — | — | EP | claimed |
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |