Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012423 | 0.81 | BACE1 (0.46) | BACE1PTPN1ALDH1A1GLANPSR1 | |
| SCHEMBL31603 | 0.77 | BACE1 (0.44) | BACE1PTPN1ALDH1A1GLANPSR1 | |
| SCHEMBL24309470 | 0.76 | BACE1 (0.42) | BACE1PTPN1GLANPSR1 | |
| SCHEMBL1403061 | 0.76 | BACE1 (0.42) | BACE1PTPN1ALDH1A1GLANPSR1 | |
| SCHEMBL20471518 | 0.76 | BACE1 (0.37) | BACE1PTPN1ALDH1A1L3MBTL1 | |
| SCHEMBL20471519 | 0.76 | BACE1 (0.37) | BACE1PTPN1ALDH1A1L3MBTL1 | |
| SCHEMBL21996563 | 0.76 | BACE1 (0.40) | BACE1PTPN1ALDH1A1POLBTSHR | |
| SCHEMBL8323836 | 0.74 | BACE1 (0.65) | BACE1ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL20351497 | 0.74 | BACE1 (0.41) | BACE1ALDH1A1GLANPSR1POLB | |
| SCHEMBL7993286 | 0.74 | BACE1 (0.41) | BACE1GLANPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107273-A1 | NEW PIPERAZINE COMPOUND AND USE THEREOF AS A HCV POLYMERASE INHIBITOR | POLR1C, POLR2E, POLR2H | BACE1 3555/4885PTPN1 1210/4885ALDH1A1 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.