Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 9/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532221 | 1.00 | CYP2C19 (0.37) | CYP2C19ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL9535238 | 0.85 | GSR (0.36) | MEN1KMT2ASMN1; SMN2THRBTP53 | |
| SCHEMBL9532679 | 0.83 | SOAT1 (0.40) | MEN1KMT2AGAAMAPTSOAT1 | |
| SCHEMBL9533213 | 0.83 | SOAT1 (0.40) | MEN1KMT2AGAAMAPTSOAT1 | |
| SCHEMBL9530755 | 0.81 | MEN1 (0.33) | MEN1KMT2AGAASMN1; SMN2THRB | |
| SCHEMBL9531838 | 0.81 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2THRBTHRA | |
| SCHEMBL9532500 | 0.76 | ALDH1A1 (0.43) | CYP2C19ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL9532215 | 0.76 | ALDH1A1 (0.43) | CYP2C19ALDH1A1SMN1; SMN2LMNATHRB | |
| SCHEMBL9534628 | 0.70 | CA12 (0.35) | ALDH1A1MEN1KMT2AGAATP53 | |
| SCHEMBL9530840 | 0.69 | CA12 (0.34) | ALDH1A1MEN1KMT2AGAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |