Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 8/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 9/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532679 | 0.88 | SOAT1 (0.40) | TXNRD1MEN1KMT2ASOAT1MAPT | |
| SCHEMBL9533213 | 0.88 | SOAT1 (0.40) | TXNRD1MEN1KMT2ASOAT1MAPT | |
| SCHEMBL9532509 | 0.85 | CYP2C19 (0.37) | MEN1KMT2ATHRBSOAT1TP53 | |
| SCHEMBL9532221 | 0.85 | CYP2C19 (0.37) | MEN1KMT2ATHRBSOAT1TP53 | |
| SCHEMBL9531838 | 0.84 | MEN1 (0.33) | MEN1KMT2ATHRBSOAT1TP53 | |
| SCHEMBL9530755 | 0.84 | MEN1 (0.33) | MEN1KMT2ATHRBSOAT1TP53 | |
| SCHEMBL9530840 | 0.76 | CA12 (0.34) | GSRTXNRD1MEN1KMT2ATHRB | |
| SCHEMBL9535226 | 0.76 | DCTPP1 (0.38) | GSRTXNRD1THRBSOAT1 | |
| SCHEMBL9531284 | 0.75 | CA12 (0.35) | GSRTXNRD1MEN1KMT2ATP53 | |
| SCHEMBL9532517 | 0.74 | CA12 (0.33) | GSRTXNRD1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | claimed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | claimed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | claimed |
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |