Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6345261 | 0.72 | ALDH1A1 (0.45) | PTPN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3084677 | 0.68 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10CRHBPCRHR2 | |
| SCHEMBL9518125 | 0.68 | PSMB5 (0.36) | PTPN1PSMB5MAPTHIF1A | |
| SCHEMBL3077632 | 0.68 | PTPN1 (0.47) | PTPN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3081954 | 0.65 | ALDH1A1 (0.41) | PTPN1ALDH1A1CYP1A2MAPTLMNA | |
| SCHEMBL5171537 | 0.63 | PTPN1 (0.45) | PTPN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9190067 | 0.62 | PTPN1 (0.46) | PTPN1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL796744 | 0.61 | KMT2A (0.44) | PTPN1ALDH1A1CYP1A2L3MBTL1HSD17B10 | |
| SCHEMBL3715467 | 0.61 | ALDH1A1 (0.36) | PTPN1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9730908 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |