Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533869 | 0.83 | GLA (0.35) | GLA | |
| SCHEMBL9530059 | 0.79 | DGAT1 (0.33) | GLA | |
| SCHEMBL10687806 | 0.74 | KMT2A (0.44) | — | |
| SCHEMBL2610502 | 0.62 | GLA (0.33) | GLA | |
| SCHEMBL7209074 | 0.60 | POLB (0.35) | — | |
| SCHEMBL30699 | 0.60 | GLA (0.41) | GLA | |
| SCHEMBL30779753 | 0.60 | GLA (0.41) | GLA | |
| SCHEMBL18510166 | 0.60 | GLA (0.41) | GLA | |
| SCHEMBL3059772 | 0.59 | POLB (0.33) | — | |
| SCHEMBL3059766 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252744-B1 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | LILLY CO ELI (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4734498-A | 3β-succinimidoazetidinones as chiral intermediates | ELI LILLY AND COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0252744-A2 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |