SCHEMBL2610502

SCHEMBL2610502

CC(=O)OC(C)(C)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12057095 0.83 BRD4 (0.31)
SCHEMBL14898349 0.83 MGLL (0.31)
SCHEMBL10074884 0.81 MGLL (0.31)
SCHEMBL13369180 0.81 BRD4 (0.30)
SCHEMBL13347914 0.80 MGLL (0.30)
SCHEMBL12057094 0.79 MAPT (0.35) GAA
SCHEMBL327851 0.79 BRD4 (0.32)
SCHEMBL2570463 0.79 MGLL (0.33) GLA
SCHEMBL6699078 0.79 MGLL (0.33) GLAGAA
SCHEMBL17777287 0.79 MGLL (0.33) GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023084449-A1 DIAMINOCYCLOPENTYLPYRIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER NOVARTIS AG (CH) 2023-05-19 WO disclosed
US-20120238621-A1 Oligomer-Calcimimetic Conjugates and Related Compounds NEKTAR THERAPEUTICS (US) 2012-09-20 US disclosed
US-20120100096-A1 CONJUGATES PF SMALL-INTERFERING NUCLEIC ACIDS NEKTAR THERAPEUTICS (US) 2012-04-26 US disclosed
US-20110237524-A1 POLYMER CONJUGATES OF AOD-LIKE PEPTIDES NEKTAR THERAPEUTICS (US) 2011-09-29 US disclosed
US-20110171166-A1 POLYMER CONJUGATES OF OSTEOCALCIN PEPTIDES NEKTAR THERAPEUTICS 2011-07-14 US disclosed
US-20110171165-A1 POLYMER CONJUGATES OF OPIOID GROWTH FACTOR PEPTIDES NEKTAR THERAPEUTICS 2011-07-14 US disclosed
US-20110171163-A1 POLYMER CONJUGATES OF ZICONOTIDE PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-14 US disclosed
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NEKTAR THERAPEUTICS (US) 2011-07-07 US disclosed
US-20100120982-A1 POLYMER-FACTOR IX MOIETY CONJUGATES NEKTAR THERAPEUTICS (US) 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110171163-A1 POLYMER CONJUGATES OF ZICONOTIDE PEPTIDES NGLY1, VIP, IAPP GLA 2903/4885GAA 1484/4885
US-20110237524-A1 POLYMER CONJUGATES OF AOD-LIKE PEPTIDES NGLY1, OCIAD1, TAP1 GLA 3137/4885GAA 1221/4885
US-20100120982-A1 POLYMER-FACTOR IX MOIETY CONJUGATES F9, F13A1, F13B GLA 289/4885GAA 371/4885
US-20110166063-A1 POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES NGLY1, CD44, IAPP GLA 2752/4885GAA 710/4885
US-20120238621-A1 Oligomer-Calcimimetic Conjugates and Related Compounds CALCR, CALCB, CALCA GLA 1111/4885GAA 1268/4885
US-20110171166-A1 POLYMER CONJUGATES OF OSTEOCALCIN PEPTIDES SOST, PTMS, ALPP GLA 68/4885GAA 1124/4885
US-20110171165-A1 POLYMER CONJUGATES OF OPIOID GROWTH FACTOR PEPTIDES OGFR, OGFRL1, OPRL1 GLA 3153/4885GAA 2443/4885
US-20120100096-A1 CONJUGATES PF SMALL-INTERFERING NUCLEIC ACIDS SLC19A1, FOLR1, SLC46A1 GLA 3802/4885GAA 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.