Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533449 | 0.95 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9531652 | 0.92 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9690827 | 0.91 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9532747 | 0.90 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9688848 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9688840 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9532878 | 0.89 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9689150 | 0.86 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9337448 | 0.86 | PPARG (0.48) | AGTR1AGTR2 | |
| SCHEMBL9690233 | 0.86 | AGTR1 (0.58) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572455-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | Astra Pharmaceuticals Limited (GB) | 1993-12-08 | — | — | EP | claimed |
| WO-1992014714-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | FISONS PLC (GB) | 1992-09-03 | — | — | WO | claimed |
| US-PP8352-P | Gypsophila L. variety -- Or | Meristem, Rahan (IL) | 1993-08-17 | — | — | US | disclosed |