Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.58 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690233 | 0.91 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9531652 | 0.89 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9533590 | 0.89 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9532808 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9532908 | 0.86 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9531497 | 0.84 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9689161 | 0.83 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9532747 | 0.83 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9688848 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9688840 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | claimed |
| EP-0500297-A1 | Substituted pyridinones and pyrimidinones as angiotensin II antagonists | FISONS plc (GB) | 1992-08-26 | — | — | EP | disclosed |