Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528272 | 1.00 | MGLL (0.57) | MGLLEPHX1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL19741321 | 0.82 | EPHX1 (0.61) | EPHX1ALDH1A1HTT | |
| SCHEMBL10667594 | 0.82 | EPHX1 (0.61) | EPHX1ALDH1A1HTT | |
| SCHEMBL17079618 | 0.80 | EPHX1 (0.67) | MGLLEPHX1ALDH1A1HTT | |
| SCHEMBL7157543 | 0.80 | EPHX1 (0.67) | MGLLEPHX1ALDH1A1HTT | |
| SCHEMBL19741475 | 0.79 | MEN1 (0.50) | EPHX1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14424473 | 0.78 | EPHX1 (0.64) | MGLLEPHX1ALDH1A1HTT | |
| SCHEMBL14873157 | 0.77 | HPGD (0.57) | EPHX1ALDH1A1HTTKDM4E | |
| SCHEMBL10662736 | 0.76 | EPHX2 (0.50) | EPHX1ALDH1A1HTT | |
| SCHEMBL22265515 | 0.76 | L3MBTL1 (0.68) | MGLLSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |