Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 8/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 7/20 | 0.55 |
| ▸ | HTR3B | O95264 | 7/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 7/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9533542 | 0.99 | HTR3A (0.54) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL9532593 | 0.81 | GAA (0.59) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL1559634 | 0.78 | MEN1 (0.74) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7435024 | 0.78 | NPC1 (0.63) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL3533984 | 0.76 | GAA (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL9531363 | 0.76 | HTR3A (0.56) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2084615 | 0.74 | HTR3A (0.55) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7435030 | 0.74 | HTR3A (0.72) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL9531967 | 0.72 | HTR3A (0.57) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7430530 | 0.72 | HTR3A (0.77) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289170-B1 | AZABICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1993-06-23 | — | — | EP | claimed |
| EP-0289170-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-11-02 | — | — | EP | claimed |