Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536338 | 0.83 | LTB4R (0.43) | LTB4RCYSLTR2CYSLTR1S1PR2S1PR1 | |
| SCHEMBL9535168 | 0.79 | CYSLTR2 (0.53) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL10687697 | 0.74 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL9532916 | 0.71 | CYSLTR2 (0.53) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL27963649 | 0.71 | CYSLTR2 (0.41) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL27943869 | 0.71 | CYSLTR2 (0.41) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL9537456 | 0.70 | LTB4R (0.58) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL9484002 | 0.70 | CYP1A2 (0.46) | CYSLTR2CYSLTR1OXER1S1PR2S1PR1 | |
| SCHEMBL9532824 | 0.69 | PPARA (0.39) | LTB4RCYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9536643 | 0.68 | TP53 (0.47) | PLA2G4APLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528957-A4 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0528957-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
| WO-1991016889-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |