Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.56 |
| ▸ | NPC1 | O15118 | 11/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5637618 | 0.92 | RAB9A (0.53) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19279180 | 0.90 | RAB9A (0.51) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL827403 | 0.84 | RAB9A (0.67) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL16859912 | 0.82 | RAB9A (0.64) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL366824 | 0.78 | RAB9A (0.81) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9228500 | 0.78 | APP (0.63) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL231307 | 0.78 | KDM4E (0.75) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29474819 | 0.78 | RAB9A (0.81) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24295138 | 0.77 | RAB9A (0.79) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3073946 | 0.77 | RAB9A (0.69) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001842-A | Amido compounds and their use as pharmaceuticals | INCYTE CORP (US) | 2007-07-18 | — | — | CN | disclosed |
| EP-0313458-B1 | IMIDAZO(2,1-B)BENZOTHIAZOLES AND THEIR ACID ADDITION SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-08-11 | — | — | EP | disclosed |