SCHEMBL827403

SCHEMBL827403

c1ccc2sc(-c3nc4ccccc4s3)nc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.67
NPC1 O15118 10/20 0.67
KDM4E B2RXH2 9/20 0.67
ALDH1A1 P00352 5/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
TP53 P04637 2/20 0.67
HSD17B10 Q99714 2/20 0.67
TSHR P16473 1/20 0.67
MAPT P10636 6/20 0.64
L3MBTL1 Q9Y468 4/20 0.64
GAA P10253 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
GLA P06280 2/20 0.64
APP P05067 2/20 0.64
TDP1 Q9NUW8 1/20 0.64
LMNA P02545 1/20 0.64
MMP9 P14780 1/20 0.64
MMP8 P22894 1/20 0.64
NPSR1 Q6W5P4 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL16859912 0.97 RAB9A (0.64) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL366824 0.88 RAB9A (0.81) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL9228500 0.88 APP (0.63) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL231307 0.88 KDM4E (0.75) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL29474819 0.88 RAB9A (0.81) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL24295138 0.86 RAB9A (0.79) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL12854008 0.86 KDM4E (0.72) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL3073946 0.86 RAB9A (0.69) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL10297868 0.86 NPC1 (0.76) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
2-Phenylbenzo[D]Thiazole SCHEMBL94005 0.86 RAB9A (0.75) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3262055-B1 WATER SOLUBLE FLUORESCENT OR COLORED DYES COMPRISING CONJUGATING GROUPS SONY GROUP CORP (JP) 2026-04-22 EP claimed
EP-4137818-B1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS SONY GROUP CORP (JP) 2025-12-10 EP claimed
EP-4590341-A1 POLYMERS WITH DUAL THERAPEUTIC AGENTS Sony Group Corporation (JP) 2025-07-30 EP claimed
EP-4590340-A1 POLYMERS WITH STEROIDS OR VITAMINS Sony Group Corporation (JP) 2025-07-30 EP claimed
EP-3440136-B1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY GROUP CORP (JP) 2025-07-23 EP claimed
US-12359071-B2 Polymeric tandem dyes with linker groups Sony Group Corporation (JP) 2025-07-15 US claimed
WO-2025047293-A1 COMPOUND, DETECTION SYSTEM, AND MEASUREMENT DEVICE ソニーグループ株式会社 2025-03-06 WO claimed
US-20250009898-A1 PYRROLOBENZODIAZEPINE CONJUGATES FOR CANCER TREATMENT SONY GROUP CORP (JP) 2025-01-09 US claimed
US-20250009786-A1 AUTOMATED SYNTHESIS OF POLYMERIC DUAL DRUGS Sony Group Corporation (JP) 2025-01-09 US claimed
US-20240294767-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS SONY GROUP CORP (JP) 2024-09-05 US claimed
US-7423133-B2 Fluorescent glycosides and methods for their use THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-09-09 US claimed
WO-2008020211-A2 BENZIMIDAZOLE, BENZOXAZOLE AND BENZOTHIAZOLE DERIVATIVES, OPTICAL FILM COMPRISING THEM AND METHOD OF PRODUCTION THEREOF CRYSOPTIX K.K. (JP) 2008-02-21 WO claimed
JP-2007528843-A 2007-10-18 JP claimed
US-20060178411-A1 Sulfonimide containing compounds and their use in polymer electrolyte membranes for electrochemical cells E. I. DU PONT DE NEMOURS AND COMPANY 2006-08-10 US claimed
US-20060177717-A1 Fluorinated sulfonamide compounds and polymer electrolyte membranes prepared therefrom for use in electrochemical cells U.S. DEPARTMENT OF ENERGY 2006-08-10 US claimed
WO-2005003081-A2 SULFONIMIDE CONTAINING COMPOUNDS AND THEIR USE IN POLYMER ELECTROLYTE MEMBRANES FOR ELECTROCHEMICAL CELLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-13 WO claimed
WO-2005001979-A2 FLUORINATED SULFONAMIDE COMPOUNDS AND POLYMER ELECTROLYTE MEMBRANES PEPARED THEREFROM FOR USE IN ELECTROCHEMICAL CELLS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-06 WO claimed
US-20040215012-A1 FLUORESCENT GLYCOSIDES AND METHODS FOR THEIR USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2004-10-28 US claimed
WO-2004019002-A2 FLUORESCENT GLYCOSIDES AND METHODS FOR THEIR USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2004-03-04 WO claimed
US-5571874-A AZOLE POLYMER, THIAZOLE RING CLOSURE, POLYAMIDE MATRIX HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 1996-11-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178411-A1 Sulfonimide containing compounds and their use in polymer electrolyte membranes for electrochemical cells HCN2, KCNN2, NHERF1 RAB9A 442/4885NPC1 1092/4885KDM4E 1901/4885
US-12359071-B2 Polymeric tandem dyes with linker groups CHRM1, IK, TMT1A RAB9A 3055/4885NPC1 4754/4885KDM4E 3566/4885
US-20060177717-A1 Fluorinated sulfonamide compounds and polymer electrolyte membranes prepared therefrom for use in electrochemical cells PEF1, NHERF1, PXMP4 RAB9A 1865/4885NPC1 741/4885KDM4E 4584/4885
US-20250009898-A1 PYRROLOBENZODIAZEPINE CONJUGATES FOR CANCER TREATMENT CHRM1, TPD52L2, H1-3 RAB9A 501/4885NPC1 3773/4885KDM4E 2855/4885
US-20250009786-A1 AUTOMATED SYNTHESIS OF POLYMERIC DUAL DRUGS CHRM1, CHRM2, H1-0 RAB9A 2135/4885NPC1 4423/4885KDM4E 2248/4885
US-20240294767-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS CHRM1, IK, TMT1A RAB9A 3055/4885NPC1 4754/4885KDM4E 3566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.